Best Case Ever 18: Anticoagulant Reversal in Trauma

Dr. Katerina Pavenski, on Anticoagulant Reversal in Trauma. A leader in Transfusion Medicine from St. Michael’s Hospital, Dr. Pavenski tells us about her Best Case Ever in which a straight forward trauma case turns into a ‘bloody disaster’, after Prothrombin Complex Concentrates (PCCs) were given in an anticoagulant reversal attempt.

In the related two-part epic episode on Antiocagulants, Transfusions & Bleeding,  Drs. Pavenski, Dr. Jeannie Callum (Head of Transfusion Medicine at Sunnybrook Hospital & Dr. Walter Himmel (also known as ‘The walking encyclopedia of EM’) cover: Indications for red cell transfusion in different clinical scenarios (GI bleed, cardiac disease, vaginal bleeding etc), Risks of transfusion including Host vs Graft Disease, TRALI & TACO, Indications for Platelet transfusion in different scenarios (hyporoliferative patients vs ITP, invasive procedures with thrombocytopenia), Managing INRs – indications for Vit K, PCC, adjusting Warfarin Dose, liver patients, Apixaban vs Rivaroxiban vs Dabigatran vs Warfarin and reversal of them, Anti-platelet medication-associated intracranial hemorrhage management, Indications for Tranexamic Acid, and much more……..

Published September, 2013

For more on Trauma Bay Pearls & Pitfalls download free eBook EM Cases Digest Vol.1 MSK & Trauma

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Dr. Helman and Dr. Pavenski have no conflicts of interest to declare.

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About the Author:

Dr. Anton Helman is an Emergency Physician at North York General in Toronto. He is an Assistant Professor at the University of Toronto, Division of Emergency Medicine and the Education Innovation Lead at the Schwartz-Reisman Emergency Medicine Instititute. He is the founder, editor-in-chief and host of Emergency Medicine Cases.

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