Ep 107 Blunt Ocular Trauma Live from The EM Cases Course

In this live podcast on Blunt Ocular Trauma from The EM Cases Course 2018 with Anna MacDonald we discuss the most important diagnoses to consider, describe how physical exam in queen while CT can misguide you, explain a simple approach to orbital compartment syndrome with retrobulbar hematoma, give you tips on lateral canthotomy, how to pick up subtle hyphemas, why sickle cell patients are high risk, describe the key clinical clues to subtle globe rupture, the role of tranexamic acid in eye bleeds and much more…

We include special guest appearances by POCUS gurus Jordan Chenkin and Rob Simard to give us tips on using POCUS in a patient who presents with their eye swollen shut as well as a bonus excerpt from the Expert Panel Discussion at The EM Cases Course on how to deal with obstructive consultants with Walter Himmel.

Podcast production, sound design & editing by Anton Helman

Written Summary and blog post by Anton Helman February 2018

Important diagnoses to consider in blunt ocular trauma 

While our minds seem to go first to orbital fractures in patients with blunt ocular trauma, our primary considerations should be the truly vision threatening emergency diagnoses:

  1. Retrobulbar hematoma with orbital compartment syndrome
  2. Hyphema
  3. Retinal detachment and
  4. Globe rupture

Physical exam is queen in blunt ocular trauma

There are few presentations in EM in which physical exam so crucial to clinching the diagnosis and guiding management as it is in blunt ocular trauma. The most common reason we miss these 4 vision threatening diagnoses are failing to do a thorough physical exam of the eye.

The first challenge often is getting a good view of the globe in a patient who presents with their eye swollen shut.

ocular trauma

There are two options. First, after adequate analgesia, apply a small piece of gauze to your fingertips and gently pry open the lid making sure not to apply any pressure to the globe. If that fails, point of care ultrasound (POCUS) may be helpful in identifying not only retinal detachment, but also globe rupture and pupillary response.

POCUS tips for globe assessment in blunt ocular trauma [9,10,11,12,13]

First, gently place a Tegaderm over the patient’s closed eyelid and then place a lot of ultrasound gel over the Tegaderm so that the ultrasound probe floats over the eye rather than pressing against the eyelid. This is to prevent pressure being placed on the globe from the high frequency linear array ultrasound probe or from having to wipe the ultrasound gel off the naked eyelid.

For pupillary response, simply shine light in the non-affected eye and look on ultrasound for pupillary dilation. Then shine the light through the eyelid of the affected eye and again, look on ultrasound for pupillary dilation.

Ask yourself the following questions:

Is the anterior chamber present or not? The absence of an anterior chamber on POCUS could be a clue that there is an anterior chamber perforation.

Is the posterior area of the globe black, round and smooth? If you see anechoic material in the posterior segment, you are probably dealing with a globe rupture associated with blood in the posterior chamber, and if the globe is not round and smooth you should suspect a globe rupture.

Is there a retinal detachment? A linear bright white anechoic segment flapping off the posterior globe is likely a retinal detachment.

What is the overall shape of the globe? In patients with retrobulbar hematoma, as the globe is compressed its shape develops from round to triangular, or what has been described as the “guitar pick sign

blunt ocular trauma

blunt ocular trauma

Physical exam checklist for blunt ocular trauma:

Visual acuity. Visual acuity should be considered the 6th vital sign for eye patients as prognosis in all of the vision threatening emergencies depends on the presenting visual acuity.

Inspection. Not only is it important to inspect all the anatomical structures of the eye for obvious trauma but to properly check for symmetry between the globes. Endophthalmos as seen in globe rupture and proptosis as seen in orbital compartment syndrome can be subtle and easily missed. The most accurate way to assess for globe symmetry crouch down at the head of the bed, or recline the chair and assess globe symmetry by viewing the globes from above the patient’s head so that the eyes are in profile, rather than face to face. Occasionally a uveal prolapse indicating a globe rupture can be subtle. Look for a small brownish blob on the surface of the eye.

Pupils and RAPD. Not only should we be checking for irregularity of the pupil found in globe rupture and PERL, but all these patients require a swinging flashlight test to assess for a relative afferent pupillary defect (RAPD) which should raise your suspiction for optic nerve ischemia in the eye trauma patient.

Visual fields. A traumatic retinal detachment can be picked up easily by checking the visual fields. This is commonly skipped over in the eye trauma patient.

Extraocular movements (EOMs). Orbital blow out fractures may cause extraocular muscle entrapment resulting in abnormal EOMs.

Slit lamp exam. When possible perform a slit lamp exam, not just for corneal abrasions and lacerations, but perhaps more importantly, for assessing the anterior chamber for cells and flair as found with a subtle hyphema.

+/- IOP. While checking the intraocular pressure (IOP) in patients with globe rupture is contraindicated, IOP should be checked for all other blunt ocular trauma patients to rule out traumatic acute glaucoma associated with hyphema and to rule out orbital compartment syndrome.

The 3 most commonly overlooked aspects of the physical exam in blunt ocular trauma leading to a missed or delayed diagnsosis are the RAPD (for orbital compartment syndrome), the visual fields (for retinal detachment) and the IOP (for orbital compartment syndrome and traumatic acute glaucoma associated with hyphema).

Orbital compartment syndrome (OCS) and retrobulbar hematoma

Divide the features of orbital compartment syndrome into mechanical and ischemic

OCS is a vision threatening elevation of intraorbital pressure that exceeds the vascular perfusion pressure of the ophthalmic artery. It can result in ischemia and irreversible vision loss if not corrected emergently. One way of conceptualizing the features of orbital compartment syndrome are to divide them into mechanical and ischemic features. The natural history of OCS starts with the mechanical features: as the retrobulbar bleed expands, it exerts force on the globe such that it will become proptotic. In addition the pressure in the globe will go up so resulting in an elevated IOP. Finally, the expanding hematoma will stretch the extraocular muscles resulting in impaired EOMs.

The ischemic features of OCS kick in as the IOP reaches a critical threshold causing the vascular perfusion pressure of the ophthalmic artery to elevate to the point that ischemia of anterior portion of the optic nerve ensues. This ischemia then results in decreased visual acuity as well as a RAPD and ultimately a blown pupil.

Pitfall: CT imaging delaying initiation of consult or lateral canthotomy.

OCS is a clinical diagnosis. While CT may clinch the diagnosis and help to rule out other traumatic injuries such as fractures, delaying vision saving management while waiting for CT results increases the chance that your patient will lose their vision permanently, as time to lateral canthotomy is a key prognostic indicator.

Lateral canthotomy: Be a Nike ninja and Just do it!

Time is eye. A Lateral canthotomy is indicated for patients with OCS within 60-120 minutes of onset of ischemic features as a temporizing measure to definitive surgical evacuation of the retrobulbar hematoma [1,2]. Similar to performing a cricothyrotomy, the biggest pitfall when it comes to performing a lateral canthotomy is the decision to do it.

Pitfall: Delaying the decision to perform a lateral canthotomy because of inexperience with the procedure.

Tips on performing a lateral canthotomy

Ensure adequate analgesia and sedation. Because the surgical field is usually very bloody, finding the lateral canthus becomes a tactile procedure and has been likened to the feel of a guitar string.

  1. Crush the lateral canthus with a clamp to devascularize the area leaving the clamp in place for one minute
  2. Feel for the guitar string-like lateral canthus with the tip of your scissors (it is not as superficial as you might think) and cut the inferior crus of the lateral canthal ligament towards the orbital rim (the rostral part of the “wishbone”)
    blunt orbital trauma

    Inferior crus of lateral canthus has been cut

  3. Check the IOP, if still elevated, cut the superior crus

Medical treatment for OCS is similar to that of acute angle closure glaucoma with mannitol, acetazolamide, pilocarpine and timolol.

Hyphema

How to pick up a subtle hyphema

Hyphema is a hemorrhage in the anterior chamber caused by bleeding from the iris or ciliary body. Usually hyphemas are easy to visualize because the blood layers out in the classic meniscus, but sometimes they are more difficult to identify.

Pitfall: Assuming there is no hyphema because you don’t see the classic meniscus.

This is when a careful anterior chamber slit lamp exam is critical. Your anterior chamber exam should be performed in the same way as you would for a suspected iritis looking for “cells and flair”. Narrow the width and height of the slit lamp beam down and angle the beam such that the light is projected from the cornea to the lens. Normally you can’t visualize the entire length of the beam. Flair occurs when you do see the length of the beam and it looks like a movie projector beam. The anterior chamber is normal clear. If you see dust-like particulate matter in the anterior chamber in a patient who has sustained trauma to the eye, those are likely red cells from a hyphema.

Pitfall: Neglecting to check the IOP in a patient with hyphema

Once you have confirmed the diagnosis of hyphema on slit lamp it is imperative to measure the IOP to rule out a traumatic acute glaucoma. The aqueous humour drains out of the anterior chamber through the trabecular meshwork. With hyphema, red cells clog up the trabecular meshwork, blocking the aqueous humor from exiting the globe, leading to elevated IOP.

Management of traumatic hyphema

Treat the symptoms with antiemetics and analgesia. Place a protective eye shield. Instruct the patient to limit eye movement (no reading or heavy physical activity) and keep the head of the bed up (instruct your patient to sleep as upright as possible) to encourage layering out of the blood. Prevent rebleeding by avoiding anticoagulants and antiplatelet agents depending on the clinical indication for these medications. In a Cochrane review on the medical management of hyphema, tranexamic acid had a significant effect in reducing the rate of secondary hemorrhage but did no improve visual outcomes [14]. For patients taking anticoagulants consideration should be given to reversing the agents as well as to oral tranexamic acid 1g tid on an individual basis. The evidence for the use of topical steroids to prevent rebleeding in hyphema is mixed but can be considered in consultation with your ophthalmologist. Medical management of traumatic acute glaucoma in the setting of hyphema is similar to nontraumatic acute angle closure glaucoma with timolol, acetazolamide, pilocarpine, mannitol etc.

While most patients settle with medical management, ophthalmologic consultation for surgical evacuation of the clot should be considered in patients with elevated IOP despite maximal medical therapy, sickle cell disease and the classic “eight-ball” grade 4 hyphema where the entire anterior chamber is filled with blood.

Beware of hyphema in patients with sickle cell disease

Note that acetazolamide is contraindicated in patients with sickle cell disease as it increases the sickling of red cells. Sickle cell patients have a high risk of rebleeding [16] and often require surgical intervention.

Globe Rupture

Key clinical clues to recognizing subtle globe rupture

Enophthalmos, edematous circumferential subconjunctival hemorrhage and irregularly shaped pupil – all clues to an underlying globe rupture

A careful assessment of globe symmetry from the head of the bed may reveal a subtle enophthalmos. Any irregularly shaped pupil (not only the classic ‘tear-drop’ shaped pupil) should raise your suspicion for a globe rupture. A large circumferential edematous traumatic subconjunctival hemorrhage as well as a uveal prolapse are concerning for a globe rupture. Remember that assessment of IOP is contraindicated in patients with suspected globe rupture.

Uveal prolapse and irregularly shaped pupil associated with globe rupture

Do not rely on CT to diagnose globe rupture

Globe rupture is a clinical diagnosis, not a radiologic one. The sensitivity of CT in a recent study out of Academic Emergency Medicine was poor only 51%–77% (depending on the radiologist) while the specificity was >97% [19]. Other studies have shown similarly poor sensitivities [20,21].

ED treatment for globe rupture starts with an eye shield. If you can not find an eyeshield in your ED consider using the bottom portion of a styrofoam cup. Analgesics, tetanus and antibiotic prophylaxis should be considered, and immediate ophthalmologic consultatiation is prudent.

Temporary eyeshield made from styrofoam cup

Take home points for blunt ocular trauma

Consider orbital compartment syndrome, hyphema, retinal detachment and globe rupture in all blunt ocular trauma patients.

Physical exam is queen. All of the vision threatening emergencies in the setting of blunt ocular trauma are made on the physical exam. Don’t forget to check for RAPD, visual fields and IOP (unless you suspect globe rupture).

Consider POCUS in patients whose eye is swollen shut and you are unable to gently pry the eyelids open.

As soon as orbital compartment syndrome has been diagnosed clinically based on mechanical and ischemic features, do not wait for CT – be a “Nike ninja” and just do the lateral canthotomy.

Just because you don’t see a meniscus, doesn’t mean a hyphema is not present. Many subtle hyphemas can only be diagnosed on a careful slit lamp exam.

Consider TXA in patients with retrobulbar hematoma and hyphema.

Beware of the sickle cell patient with hyphema.

Do not rely on CT to rule out globe rupture. Globe rupture is a clinical diagnosis and can be subtle. Look for subtle enophthalmos, any irregularity in the pupil, large subconjunctival hemorrhage and uveal prolapse.

Drs. Helman and MacDonald have no conflicts of interest to declare.

References

  1. Vassallo S, Hartstein M, Howard D, et al. Traumatic retrobulbar hemorrhage: emergent decompression by lateral canthotomy and cantholysis. J Emerg Med. 2002;22(3):251-256.
  2. Winterton JV, Patel K, Mizen KD. Review of management options for a retrobulbar hemorrhage. J Oral Maxillofac Surg. 2007;65(2):296-299.
  3. Babineau MR, Sanchez LD. Ophthalmologic procedures in the emergency department. Emerg Med Clin North Am. 2008;26(1):17-34.
  4. Logothetis HD, Leikin SM, Patrianakos T. Management of anterior segment trauma. Dis Mon. 2014;60(6):247-253.
  5. Khaw PT, Shah P, Elkington AR. Injury to the eye. BMJ. 2004;328(7430):36-38.
  6. Brandt MT, Haug RH. Traumatic hyphema: a comprehensive review. J Oral Maxillofac Surg. 2001;59(12):1462-1470.
  7. Walton W, Von Hagen S, Grigorian R, et al. Management of traumatic hyphema. Surv Ophthalmol. 2002;47(4):297-334.
  8. Sung EK, Nadgir RN, Fujita A, et al. Injuries of the globe: what can the radiologist offer? Radiographics. 2014;34(3):764- 776.
  9. Blaivas M, Theodoro D, Sierzenski PR. A study of bedside ocular ultrasonography in the emergency department. Acad Emerg Med. 2002;9(8):791-799.
  10. Blaivas M. Bedside emergency department ultrasonography in the evaluation of ocular pathology. Acad Emerg Med. 2000;7(8):947-950.
  11. Roque PJ, Hatch N, Barr L, et al. Bedside ocular ultrasound. Crit Care Clin. 2014;30(2):227-241.
  12. Frasure SE, Saul T, Lewiss RE. Bedside ultrasound diagnosis of vitreous hemorrhage and traumatic lens dislocation. Am J Emerg Med. 2013;31(6):1002.e1001-e1002.
  13. Theoret J, Sanz GE, Matero D, et al. The “guitar pick” sign: a novel sign of retrobulbar hemorrhage. CJEM. 2011;13(3):162- 164. (Case report)
  14. Gharaibeh A, Savage HI, Scherer RW, et al. Medical interventions for traumatic hyphema. Cochrane Database Syst Rev. 2013;12:CD005431.
  15. Rahmani B, Jahadi HR. Comparison of tranexamic acid and prednisolone in the treatment of traumatic hyphema. A randomized clinical trial. Ophthalmology. 1999;106(2):375-9.
  16. Rahmani B, Jahadi HR, Rajaeefard A. An analysis of risk for secondary hemorrhage in traumatic hyphema. Ophthalmology. 1999;106(2):380-385.
  17. Santen SA, Scott JL. Ophthalmologic procedures. Emerg Med Clin North Am. 1995;13(3):681-701. (Review)
  18. Kearns P. Traumatic hyphaema: a retrospective study of 314 cases. Br J Ophthalmol. 1991;75(3):137-141.
  19. Crowell EL, Koduri VA, Supsupin EP, et al. Accuracy of Computed Tomography Imaging Criteria in the Diagnosis of Adult Open Globe Injuries by Neuroradiology and Ophthalmology. Acad Emerg Med. 2017;24(9):1072-1079.
  20. Yuan WH, Hsu HC, Cheng HC, et al. CT of globe rupture: analysis and frequency of findings. AJR Am J Roentgenol. 2014;202(5):1100-7.
  21. Arey ML, Mootha VV, Whittemore AR, Chason DP, Blomquist PH. Computed tomography in the diagnosis of occult open-globe injuries. Ophthalmology. 2007;114(8):1448-52.
  22. Messman, A. M. (2015). Ocular Injuries: New Strategies In Emergency Department Management. Emergency Medicine Practice, 1–27. Retrieved from https://www.ebmedicine.net

Other FOAMed Resources on Blunt Ocular Trauma

Life in the Fast Lane on Blunt Eye Trauma

First10EM outlines simple approach to Retrobulbar Hematoma and Lateral Canthotomy

Oliver Flower video from SMACC Chicago on Lateral Canthotomy

ERCast reviews Management of Hyphema

Now Test Your Knowledge:

1. A 32 year old woman presents after being hit in her left eye with a baseball. On ultrasound, you see that the globe is compressed and triangular. What is the most likely diagnosis?

A Retrobulbar hematoma

B Hyphema

C Retinal detachment

D Globe rupture

Answer: A

In patients with retrobulbar hematoma, as the globe is compressed, its shape becomes triangular. This is also known as the “guitar pick sign”.

2. A 44 year old woman presents to the emergency department after suffering a traumatic blow to her right eye. On ultrasound examination, you see anechoic material in the posterior area of the globe. Which of the following physical exams would you avoid?

A Pupils and RAPD

B Extraocular movements of the eyes

C Intraocular pressure

D Visual fields

Answer: C

The ultrasound findings of anechoic material in the posterior area of the globe is associated with globe rupture and blood in the posterior chamber. Checking the IOP is contraindicated in patients with globe rupture.

3. When assessing a patient who suffered a blunt ocular trauma, what information on exam makes you concerned that this could be a late presentation of orbital compartment syndrome?

A Unilateral proptosis

B Elevated IOP

C Impaired EOM

D Decreased visual acuity

Answer: D

Features of orbital compartment syndrome can be categorized into mechanical and ischemic causes. Mechanical features include proptotic globe, elevated IOP, and impaired EOM. Ischemic features include decreased visual acuity, RAPD, and a blown pupil.

4. You are assessing a 40 year old man who presented after getting hit in the face with a baseball bat 4 hours ago. His right eye is swollen and appears proptotic. He has decreased visual acuity and increased IOP to that eye. Which of the following management options would you pursue first?

A Mannitol

B Acetazolamide

C CT scan of the eye

D Lateral canthotomy

Answer: D

A lateral canthotomy is indicated for patients with OCS within 60-120 minutes of onset of ischemic features of orbital compartment syndrome. Remember that time is eye! Delaying vision saving management while waiting for CT results increases the chance that your patient will lose their vision permanently.

5. Which of the following exam findings is NOT associated with a hyphema?

A Irregularly shaped pupil

B Cells and flare on slit lamp exam

C Layering of the red blood cells in the anterior chamber

D Increased IOP

Answer: A

Hyphema is a hemorrhage in the anterior chamber that classically present with a meniscus due to blood layering. On slit lamp exam, cells and flair can be seen. Always measure the IOP as red cells can clog up the trabecular meshwork, blocking the aqueous humor from exiting the globe, leading to acute glaucoma. Irregularly shaped pupil is seen in globe rupture.

6. A 16 year old teenage boy with a history of sickle cell disease presents after be struck in his right eye. You see layering of red blood cells in the anterior chamber and find his IOP to be elevated. Which of the following medications would you avoid?

A Timolol

B Acetazolamide

C Pilocarpine

D Mannitol

Answer: B

Acetazolamide is contraindicated in patients with sickle cell disease as it increases the sickling of red cells.

7. In a patient with hyphema, which of the following is NOT an indication for urgent surgical consultation for consideration of evacuation of the clot?

A Elevated IOP despite maximal medical therapy

B Sickle cell disease

C Presence of flare on slit lamp exam

D Grade 4 hyphema

Answer: C

Presence of flare is when the beam on slit lamp is projected from the cornea to the lens. The anterior chamber is normally clear. This finding alone is not an indication for surgical intervention.

8. Which of the following is NOT a finding on exam suspicious for globe rupture?

A Enophthalmos

B Linear bright white anechoic segment flapping off the posterior globe

C Circumferential edematous traumatic subconjunctival hemorrhage

D Uveal prolapse

E Irregularly shaped pupil

Answer: B

Linear bright white anechoic segment flapping off the posterior globe is an ultrasound finding seen in retinal detachment. The remaining choices are all exam findings suspicious of globe rupture.

9. A 50 year old man presents to the emergency department after suffering a traumatic blow to his left eye. On ultrasound, the anterior chamber is absent. What is the most likely diagnosis?

A Retrobulbar hematoma

B Hyphema

C Retinal detachment

D Anterior chamber perforation

Answer: D

The finding of an absent anterior chamber is suggestive of anterior chamber perforation.

10. A 30 year old man presents with all the clinical signs of globe rupture. You would manage this by immediately doing all of the following except?

A Antibiotics

B Optho consult

C Analgesics

D CT scan

Answer: D

Globe rupture is a clinical diagnosis not a radiologic one. Do not rely on CT for the diagnosis.

11. A 20 year old male presents to your ED with proptosis, elevated IOP and impaired EOMs. You suspect orbital compartment syndrome. Your next move is?

A Immediate CT scan

B Find the lateral canthus and perform a lateral canthotomy

C Examine for ischemic features

D Eye patch

Answer: C

A Lateral canthotomy is indicated for patients with OCS within 60-120 minutes of onset of ischemic features. These features are:

– Decreased visual acuity 

– RAPD

– Blown pupil

12. Your patient with orbital compartment syndrome develops ischemic features and you opt to do a lateral canthotomy. You find the inferior crus and cut it. Your next move is?

A Re-examine the EOMs

B Feel for the superior crus

C Check the IOP

D Give blood products

Answer: C

Check the IOP after cutting the inferior crus; if still elevated, cut the superior crus.

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About the Author:

Dr. Anton Helman is an Emergency Physician at North York General in Toronto. He is an Assistant Professor at the University of Toronto, Division of Emergency Medicine and the Education Innovation Lead at the Schwartz-Reisman Emergency Medicine Instititute. He is the founder, editor-in-chief and host of Emergency Medicine Cases.

One Comment

  1. Dr Ian Light April 10, 2018 at 8:31 pm - Reply

    Timolol needs to avoided in asthma and COPD Latanoprost is safer .
    Can you use TMX pledgers in lateral canthotomy to reduce ooze of blood ?

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