Ep 213 Update in Management of Status Epilepticus

Convulsive status epilepticus is one of the most morbid neurologic emergencies we manage in the ED, and outcomes depend far more on speed than drug selection. Like ventricular fibrillation, each minute of ongoing convulsions worsens hypoxia, acidosis, cardiovascular instability, and neuronal injury, while making seizures progressively harder to terminate. Modern definitions are intentionally time-compressed to force early, parallel, clock-anchored action. Any patient still convulsing when you reach the bedside should be treated as evolving status epilepticus. In this EM Cases podcast with Dr. Sara Gray, we take a practical, time-based approach to convulsive status epilepticus, focusing on early, adequately dosed benzodiazepines, avoiding common escalation and dosing pitfalls, anticipating post-ictal cardiovascular collapse, and knowing when to escalate to second-line agents, airway control, and anesthetic-dose therapy. We also address the transition to non-convulsive status epilepticus and how to recognize ongoing seizures when EEG is not immediately available. We answer questions such as: Why does time to first benzodiazepine matter more than the drug or route? What critical actions should occur in parallel with the first dose? What are 3 key actions to do in parallel with the first benzodiazepine? Why is underdosing second-line antiseizure medications—especially levetiracetam—a common and dangerous pitfall? When should persistent seizures trigger intubation and anesthetic-dose therapy? How can we identify non-convulsive status epilepticus once tonic-clonic activity stops? And many more (we also include a high yield status epilepticus management algorithm in the show notes!)... If you find EM Cases helpful in your clinical practice, please consider supporting our work so we can continue producing free, high-quality emergency medicine education for clinicians around the world. Make a donation here: https://emergencymedicinecases.com/donation/

ECG Cases 60 – ACLS arrhythmia pitfalls, part 3: unstable tachycardia, cardiovert?

This is the third in a series of blog posts on the pitfalls of ACLS algorithms for adults with a pulse, and how a systematic approach to 12-lead ECG can help with ECG acquisition, interpretation, and application. The first looked at unstable bradycardia, the second stable bradycardia, and this one will look at unstable tachycardia. The ACLS algorithm for unstable tachyarrhythmia is simple: immediate cardioversion. This works well if it is a primary tachyarrythmia that is causing the instability (eg SVT or VT), but there are a number of pitfalls in this assumption. ECG acquisition: is it actually a tachy-arrhythmias? Artifact can mimic a tachy-arrhythmia. This can be identified by unaffected leads recorded at the same time, and narrow QRS complexes marching through the noise ECG interpretation: is the tachy-arrhythmia a primary electrical problem? There are other tachycardias in unstable patients that may fail to respond to cardioversion: AF (irregularly irregular rhythm), where the patient’s instability may be related to a secondary cause Sinus tachycardia (in response to a secondary cause): can best be identified by upright P waves in II and biphasic P waves in V1. ECG application: Is the rhythm causing the instability, or is there a secondary cause – including one that might be revealed by the 12-lead, like hyperkalemia or occlusion MI? For live and highly interactive ECG courses to elevate your skills - including online courses, or an in-person pre-conference course at CAEP, go to www.heartsECGcourse.com

Ep 212 PECARN Febrile Young Infant Prediction Tool: When To Safely Forgo LP and Empiric Antibiotics

If you’ve been practicing EM for more than a decade, your approach to the febrile young infant has (appropriately) evolved. For years, the default was LP + empiric antibiotics + admission for almost everyone. That approach prevented missing meningitis, but at the cost of a lot of harm: invasive testing, unnecessary antibiotics, and hospitalization-related complications. The modern approach is a paradigm shift toward risk stratification, biomarkers, and shared decision-making, while still respecting one immutable truth: Missing neonatal bacterial meningitis can be catastrophic. This episode revisits the framework from a prior EM Cases episode and updates it with a landmark study that directly informs how far we can safely go—especially in the 0–28 day group, with the father of multiple well-known PECARN rules Dr. Nathan Kuppermann and lead author Dr. Brett Burstein...

EM Quick Hits 70 MedMal Cases Upper Back Pain, Traumatic Pneumothorax/Hemothorax Decision Making, Risk Stratification of ICH for Consultation, Post-Circumcision Bleeds, IV Contrast Allergy, Emotional Contagion

In this month's EM Quick Hits podcast: Mike Weinstock discusses with Anton a case of upper back pain in this month's Medmal Cases, Andrew Petrosoniak on traumatic pneumothorax and hemothorax decision making: risk stratification, imaging cutoffs and chest tube choices, Justin Morgenstern on brain injury guidelines risk stratification for neurosurgical consult, repeat imaging and admission, Andrew Tagg on management of post-circumcision bleeding and when to escalate care, Hans Rosenberg & Ariel Hendin on evaluation and management of CT contrast allergy and why steroids are out, Shawn Seregren on emotional contagion in resuscitation teams: how tone, pace and volume of your voice and body language effect team rescucitation dynamics and outcomes...

Top 10 Best of EM Cases 2025

As we close the chapter on 2025, I want to extend a heartfelt thank you to the EM Cases community—our listeners and readers around the world—whose engagement, feedback, and trust continue to shape how we teach and learn Emergency Medicine. None of this would be possible without the extraordinary efforts of our podcast guest experts, the EM Cases content and production team, our partners at SREMI, our advisory board, the University of Toronto, and those who support us through donations and attending the EM Cases Summit. What follows is the Best of EM Cases 2025: a curated collection of the highest-impact emergency medicine education from the past year, chosen by learner engagement, feedback, and a few personal favorites...

Ep 211 Thyrotoxicosis and Thyroid Storm: Recognition and Management

In this Part 2 of our 2-part podcast series on thyroid emergencies Anton, Dr. George Willis and Dr. Alyssa Louis answer questions such as: When a patient presents with “sepsis without a source,” what bedside features should trigger you to prioritize thyrotoxicosis? How can PoCUS help you decide whether tachycardia is dangerous — or lifesaving — before starting β-blockade? Why can TSH and free T4 be falsely reassuring in a crashing patient, and what labs actually matter early? In which patients does propranolol increase the risk of cardiovascular collapse — and why is esmolol the safer first line medication? Why does the order β-blocker → thionamide → steroid → iodine matter, and what happens if you get it wrong? When is not giving a β-blocker the safest decision in thyroid storm, even in a profoundly tachycardic patient? In an agitated, hyperthermic patient with thyrotoxicosis, why might intubation be more dangerous than helpful in the first hour? How does amiodarone-induced thyrotoxicosis fundamentally change your management — and why can iodine make it worse? and many more...

Ep 210 Decompensated Hypothyroidism Recognition and Management

In the ED, we regularly care for sick patients presenting acutely with abnormal vital signs, altered mental status, and end organ dysfunction. Oftentimes, the culprit ends up being sepsis, or overdose, or organ failure. But it is important that we consider rarer endocrine presentations like decompensated hypothyroidism. In this Part 1 of this two-part podcast with Dr George Willis and Dr Alyssa Louis, we answer questions like: Why is the term myxedema coma a misnomer and should be abandoned? How can we differentiate between sepsis or environmental hypothermia or toxidrome from decompensated hypothyroidism at the bedside? When is it appropriate to order a TSH, a T4 and T3? What are the most important life-threatening triggers that need to be addressed in patients with decompensated hypothyroidism? Why is it important to test for cortisol levels and consider stress-dose steroids in all patients with decompensated hypothyroidism? Why is endotracheal intubation particularly dangerous in decompensated hypothyroidsm? What is the best way to manage hypothermia? Why is the order of medications for treatment of decompensated hypothyroidism so important? and many more... Please consider a donation to EM Cases to ensure continuing Free Open Access Medical Education: https://emergencymedicinecases.com/donation/

ECG Cases 59 – ACLS Dysrhythmia Pitfalls Part 2: Stable Bradycardia? Or Dangerous Bradycardia Requiring Pacemaker?

Five patients presented with bradycardia and normal blood pressure. How does ECG interpretation change management? Despite apparent stability, which require immediate treatment and which require admission for a pacemaker?...

EM Quick Hits 69 Pediatric Urinary Retention & Acute Transverse Myelitis, Post-Dural Puncture Headache, Med Mal Cases: Clenched Fist Injury, IV Thrombolysis for Minor Stroke, EM Leadership Spotlight #4

On this month's EM Quick Hits podcast: Deborah Schonfeld on the differential diagnosis and work up of pediatric urinary retention & acute transverse myelitis, Jesse McLaren on his Tryptic Approach to Occlusion MI Diagnosis, Matthew McArthur on recognition and management of post-dural puncture headache, Joseph Yasmeh on Med Mal Cases: Clenched fist injury, Brit Long on IV thrombolysis for minor strokes and Victoria Myers & Lauren Westafer on mentorship and what it means to be a physician leader... Please consider a donation to EM Cases to support high quality Free Open Access Medical Education here: https://emergencymedicinecases.com/donation/

Ep 209 Nondisabling Stroke Recognition and Management

In this Part 2 or our 2-part podcast update on ED stroke management with Dr. Katie Lin and Dr. Walter Himmel we explore non-disabling strokes, where symptoms are mild enough that patients can continue daily activities if deficits persist. Yet, non-disabling does not mean benign. Non-disabling strokes occupy the same ischemic continuum as TIAs and carry a substantial risk of early recurrence with disabling stroke. In this EM Cases podcast we answer questions such as: Which patients with non-disabling stroke can safely go home with prompt follow-up and which require urgent investigation or admission? Which stroke mimics do we need to be on the look out for and how do we identify them at the bedside? How dangerous is thrombolysis in a patient with presumed stroke who turns out to be a stroke mimic? What are the key distinguishing features between a stroke and functional neurologic disorder? What are the most common causes of stroke in young people that we commonly miss? How does stroke etiology dictate the management pathway? What are the indications for carotid endarterectomy in patients with non-disabling stroke and what is the ideal timing of the endarderectomy? When is dual antiplatelet therapy vs single antiplatelet thereapy vs anticoagulant therapy indicated? What is the best medication strategy for the patient on a DOAC for atrial fibrillation who presents to the ED with a non-disabling stroke? For patients not on a DOAC for atrial fibrillation who come in with a stroke, when is it safe to start anticoagulation? and many more... Make A Donation: https://emergencymedicinecases.com/donation/.com

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